School of Chemical Engineering

Crystallization and Particle Technology
Systems Engineering

Yash Barhate
Graduate Research Assistant
email@purdue.edu

LinkedIn Google Scholar

Project Description

My research focuses on model-based and model-free approaches for process design, optimization, and control of continuous crystallization processes primarily for pharmaceutical applications.

Experience

  • Undergraduate student researcher - Cavitation research lab, Institute of chemical technology, Mumbai (May 2018- May 2020)
  • Graduate teaching assistant - Design of staged seperation processes, Purdue University (Fall 2022)
  • Graduate teaching assistant - Pharmaceutial API Process Development and Design, Purdue University (Fall 2023)

Publications and Presentations

Journal Publications

  • Barhate Y., Kilari H., Wu W., Nagy Z.K., (2023) Population balance model enabled digital design and uncertainty analysis framework for continuous crystallization of pharmaceuticals using an automated platform with full recycle and minimal material use. Chemical Engineering Science.

Conference Presentations

  • Digital design framework for the continuous crystallization of Diphenhydramine hydrochloride. Yash Barhate, Hemalatha Kilari, Wei-Lee Wu, Jaron Mackey, Haotang Li, Zoltan Nagy. AICHE Annual Meeting , Phoenix 2022
  • Digital design framework for pharmaceutical crystallization processes – A case study for continuous cooling crystallization of Diphenhydramine hydrochloride. Yash Barhate, Hemalatha Kilari, Wei-Lee Wu, Zoltan Nagy. International Symposium on Industrial Crystallization (ISIC) , Glasgow 2023
  • Model-based experimental design procedure for robust digital twin development for continuous crystallization systems. Yash Barhate, Hemalatha Kilari, Zoltan Nagy. AICHE Annual Meeting, Orlando 2023

Education